The solubility of solid pharmaceutical compounds is a critical factor that their bioavailability, effectiveness, safety, and quality. Solubility determines how quickly and efficiently a drug can dissolve and be absorbed into the body, which can affect its bioavailability, therapeutic efficacy, and potential side effects. Therefore, understanding solubility is a crucial step in drug development, formulation, and dosage selection, as well as for ensuring the quality of medications throughout their shelf life.