Researchers at the DWI – Leibniz-Institute for Interactive Materials, Aachen, Germany have developed injectable microgels that can be magnetically oriented within a larger hydrogel to regenerate various types of tissue. The team began by functionalizing a material called six-arm poly(ethylene oxide-stat-propylene oxide) with acrylate groups, which can be broken down and removed by the kidney. Superparamagnetic iron oxide nanoparticles, which can align to an applied magnetic field, were mixed into the functionalized material. The team then crosslinked this mixture with UV-light to form microgels. To increase the contact surface with cells, a peptide containing the RGD sequence, a focal adhesion point for cells, was grafted onto the microgels. This innovative strategy provides a promising tool for tissue regeneration.