September 26, 2023
How to quantify cell concentration with TURBIDI.T™?
Growing demands for quicker cell quantification methods push beyond traditional cell counting chambers, prompting innovative solutions that facilitate accurate counting while diminishing time. Turbidity, reflecting solution cloudiness in the presence of light scatterers, emerges as an effective means to accelerate cell quantification. In this application note, a strong correlation was established between turbidity (FTU) of a S. cerevisiae culture solution and cell numbers (cells/mL) counted with a conventional cell counting chamber...
September 8, 2023
How do the µ-volume and the macro-volume sample holders of the ElastoSens™ Bio compare?
The μ-volume sample holder was developed as an alternative to the macro-volume sample holder for projects where sample volume is restricted. Due to the non destructive nature of the technology, the sample can be kept in both sample holders and retested multiple times to follow the mechanical profile over time of the sample in controlled environments. One important difference is that the μ-volume sample holder was designed to fit in a 12-well plate for easy sample incubation, and completely autoclavable (made of stainless steel) to better maintain sample sterility cellularized hydrogels ...
September 8, 2023
How to introduce a sample into the µ-volume sample holder of the ElastoSens™ Bio?
The ElastoSens™ Bio is a compact analytical instrument that measures the viscoelastic properties of soft materials following easy and quick steps guided by the Soft Matter Analytics™ App. Prior to testing, the sample to be measured needs to be inserted into the available sample holders specifically designed for the ElastoSens™ Bio. This step plays a key role in ensuring the quality of the data obtained from the instrument. The μ-volume sample holder was developed for applications in which sample volume is limited, such as for natural polymers, blood and plasma ...
July 18, 2023
How to monitor yeast growth in a bioreactor with TURBIDI.T™?
In the realm of bioengineering and biotechnology, cells serve as catalysts for the production of diverse valuable products, such as biofuels, pharmaceuticals, antibodies, industrial enzymes, and bio-based chemicals [1]. Within this context, yeast, a widely utilized microorganism, plays a pivotal role. Monitoring yeast growth is of utmost importance to ensure optimal conditions and productivity in biotechnological processes [2]. Traditionally, spectrophotometric analysis has been used to assess the optical density at 600 nm (OD600nm) by measuring the absorption of light by the yeast ...
July 18, 2023
How to measure the sedimentation of suspended particles with TURBIDI.T™?
The sedimentation kinetics of suspended particles provides crucial information for optimizing manufacturing and infrastructure across industries, while also contributing to the design of drugs and cell therapies. Turbidimetry is a quick and nondestructive method to precisely determine the sedimentation kinetics of suspended particles. The decrease in turbidity of silica particles in distilled water as a function of time was obtained with high precision using the TURBIDI.TTM. This curve gives information about the sedimentation behavior and rate of the suspended particles ...
July 11, 2023
How to measure particle size in a liquid sample with TURBIDI.T™?
The determination of particle size is important in many fields, such as life sciences (nanomedicine, drug delivery, tissue engineering, bioanalysis), chemical, environmental sciences and industries. Turbidimetry is a quick and nondestructive method to estimate particle size following an easy-to-follow procedure. Curves of turbidity vs silica particle concentration in distilled water of various sizes were obtained with high precision using the TURBIDI.TTM. These curves can be used to build a reference curve for the determination of particle size.
May 26, 2023
How to measure the concentration of particles in a liquid sample with TURBIDI.T™?
A suspension is a mixture in which solid particles (organic or inorganic in nature) are dispersed in a liquid medium, but not dissolved. Suspensions are usually opaque or cloudy and can settle over time due to gravity. They have a broad range of applications and are present in various industrial processes, such as chemical, pharmaceutical, food and beverage, and environmental industries. During the production of pharmaceutical formulations for example, professionals may measure particle concentration to assess whether particles have aggregated or formed larger clusters to optimize the process and ensure product quality.
March 20, 2023
TURBIDI.T™ | Validation of wide range turbidity measurements
TURBIDI.T™ is a technology that accurately measures the turbidity of solutions across a broad spectrum. Its effectiveness has been tested against an established turbidimeter and the results have indicated that both technologies yield consistent measurements for formazin solutions of varying concentrations.