July 18, 2023
How to monitor yeast growth in a bioreactor with TURBIDI.T™?
In the realm of bioengineering and biotechnology, cells serve as catalysts for the production of diverse valuable products, such as biofuels, pharmaceuticals, antibodies, industrial enzymes, and bio-based chemicals [1]. Within this context, yeast, a widely utilized microorganism, plays a pivotal role. Monitoring yeast growth is of utmost importance to ensure optimal conditions and productivity in biotechnological processes [2]. Traditionally, spectrophotometric analysis has been used to assess the optical density at 600 nm (OD600nm) by measuring the absorption of light by the yeast ...
March 20, 2023
TURBIDI.T™ | Validation of wide range turbidity measurements
TURBIDI.T™ is a technology that accurately measures the turbidity of solutions across a broad spectrum. Its effectiveness has been tested against an established turbidimeter and the results have indicated that both technologies yield consistent measurements for formazin solutions of varying concentrations.
October 25, 2021
Towards a standard method for mechanically characterizing soft organs
In October, our focus was on the mechanical characterization of soft organs. Understanding the mechanical properties of tissues is crucial for advancements in tissue engineering and regenerative medicine. However, measuring the mechanical properties of soft tissues is not straightforward and often involves customized approaches. Standardized and reproducible methods are needed to accurately characterize the mechanical properties of soft organs. By establishing consistent measurement techniques, researchers can gain a deeper understanding of tissue mechanics and develop effective treatments and therapies.
October 6, 2021
Measuring the viscoelastic properties of lungs through complementary techniques
Mechanical testing of soft tissues and organs is crucial for biomaterial development. A study from the University of Massachusetts compared different testing techniques and evaluated the impact of sample freezing on lung tissue. The findings highlighted variations in mechanical properties depending on the technique used and showed a slight difference between fresh and frozen samples. Standardized testing methods are necessary for reliable measurements and advancements in tissue engineering.
April 12, 2021
When mechanical testing slows down the development of bioengineered vascular grafts
Blood vessels play a vital role in the circulation of blood throughout the body, working in conjunction with the heart. Their mechanical behavior, characterized by viscoelastic properties, is crucial for efficient blood flow. Understanding and characterizing the mechanical properties of blood vessels is essential, particularly in the development of vascular grafts. A team of researchers from Laval University, led by Prof. Diego Mantovani, recently published a review article discussing the significance of proper mechanical characterization and summarizing the existing methods in the field.
January 30, 2021
Blood coagulation analysis using ElastoSens™ Bio
The viscoelastic properties of coagulating blood can be correlated with several diseases and genetic conditions that affect the natural blood coagulation process including bleeding disorders, hemophilia, rare factor deficiencies, von Willebrand disease and platelet function disorders. Therefore, the evaluation of blood clot properties can be valuable for the study, diagnosis and eventually treatment of these diseases.
January 30, 2021
ElastoSens™ Bio: A tool for hydrogel formulation
Natural polymers such as collagen, fibrin, chitosan, and agarose exhibit superior biological activity when compared to synthetic materials and so, they are often used to entirely or partially compose hydrogels. The formation of a hydrogel is governed by the development of physical or chemical bonds between the polymeric chains and depends strongly on its formulation. The formulation of a hydrogel includes the selection and dosage of the polymer, solvent and crosslinking agent (when present).