March 1, 2022
An inorganic biomaterial with great hemostatic potential
Scientists from Dalhousie University, led by Dr. Mark Joseph Filiaggi, investigated the sodium polyphosphate (NaPP) polymer as a potential hemostatic agent. They tested six formulations of the biomaterial, with varying degrees of polymerization and types of divalent cations. The hemostatic potential of these formulations was evaluated using various blood clotting assays. The biomaterial was mixed with coagulation reagents and recalcified blood or plasma in a tube, which was then shaken to visually assess blood or plasma flow. The clotting time was noted as the time required to achieve no flow. Surgifoam®, a commercial hemostatic agent, was used as a control.
May 10, 2021
In addition to vaccines, the viscoelasticity of coagulating blood can help optimizing outcomes in COVID-19 patients
In a recent study published in the Critical Care Medicine Journal, researchers from Western Michigan University, the University of Texas, and healthcare-related offices across the United States investigated the relationship between COVID-19 and blood coagulation disorders. They found that analyzing the viscoelastic changes in coagulating blood can provide personalized information on a patient's coagulation state, offering valuable insights for treatment optimization. The study highlights the importance of a personalized patient-oriented approach due to the diverse clinical profiles observed in COVID-19 cases.
January 30, 2021
Blood coagulation analysis using ElastoSens™ Bio
The viscoelastic properties of coagulating blood can be correlated with several diseases and genetic conditions that affect the natural blood coagulation process including bleeding disorders, hemophilia, rare factor deficiencies, von Willebrand disease and platelet function disorders. Therefore, the evaluation of blood clot properties can be valuable for the study, diagnosis and eventually treatment of these diseases.